Description: Dynamic Brain : An Exploration of Neuronal Variability and Its Functional Significance, Hardcover by Ding, Mingzhou (EDT); Glanzman, Dennis (EDT), ISBN 0195393791, ISBN-13 9780195393798, Brand New, Free shipping in the US It is a well-known fact of neurophysiology that neuronal responses to identically presented stimuli are extremely variable. This variability has in the past often been regarded as "noise." At the single neuron level, interspike interval (ISI) histograms constructed during either spontaneous or stimulus evoked activity reveal a Poisson type distribution. These observations have been taken as evidence that neurons are intrinsically "noisy" in their firing properties. In fact, the use of averaging techniques, like post-stimulus time histograms (PSTH) or event-related potentials (ERPs) have largely been justified based on the presence of what was believed to be noise in the neuronal responses. More recent attempts to measure the information content of single neuron spike trains have revealed that a surprising amount of information can be coded in spike trains even in the presence of trial-to-trial variability. Multiple single unit recording experiments have suggested that variability formerly attributed to noise in single cell recordings may instead simply reflect system-wide changes in cellular response properties. These observations raise the possibility that, at least at the level of neuronal coding, the variability seen in single neuron responses may not simply reflect an underlying noisy process. They further raise the very distinct possibility that noise may in fact contain real, meaningful information which is available for the nervous system in information processing. To understand how neurons work in concert to bring about coherent behavior and its breakdown in disease, neuroscientists now routinely record simultaneously from hundreds of different neurons and from different brain areas, and then attempt to evaluate the network activities by computing various interdependence measures, including cross correlation, phase synchronization and spectral coherence. This book examines neuronal variability from theoretical, experimental and clinical perspectives.
Price: 190.51 USD
Location: Jessup, Maryland
End Time: 2024-11-23T05:11:51.000Z
Shipping Cost: 0 USD
Product Images
Item Specifics
Return shipping will be paid by: Buyer
All returns accepted: Returns Accepted
Item must be returned within: 14 Days
Refund will be given as: Money Back
Return policy details:
Book Title: Dynamic Brain : An Exploration of Neuronal Variability and Its Fu
Number of Pages: 400 Pages
Language: English
Publication Name: Dynamic Brain : an Exploration of Neuronal Variability and Its Functional Significance
Publisher: Oxford University Press, Incorporated
Subject: Neuroscience, Life Sciences / Neuroscience, Life Sciences / Anatomy & Physiology (See Also Life Sciences / Human Anatomy & Physiology), Statistics
Item Height: 1 in
Publication Year: 2011
Type: Textbook
Item Weight: 91.7 Oz
Subject Area: Science, Psychology, Medical
Author: Dennis Glanzman
Item Length: 6.3 in
Item Width: 9.3 in
Format: Hardcover
